Nann Fangue seeks to understand the physiological specializations that allow animals to survive and thrive in complex environments. She studies aquatic species, including sturgeon and salmonids, to understand whether these organisms have sufficient physiological capacity or plasticity to maintain successful performance in the face of anthropogenic environmental perturbations such as climate change. This research couples molecular, biochemical, physiological, and whole-organism measures of performance framed in an ecological context, to elucidate connections between environment, physiology, and ecosystem function.